Germ Cell Biology
Developmental Programming
Epigenetic inheritance
2023
Pei Y*, Risal S*, Jiang H, Lu HJ, Lindgren E, Stener-Victorin E#, Deng Q#
Commun Biol 6, 69 (2023). doi: 10.1038/s42003-022-04362-0
Luo Q, Pui HP, Chen J, Yu L, Jannig PJ, Pei Y, Zhao LX, Chen X, Petropoulos S, Ruas JL, Wu J, Deng Q
Cell Reports 42, 112021, January 31, 2023. doi: 10.1016/j.celrep.2023.112021
2022
Pui HP, Deng Q
Methods Mol Biol. 2022; 2490:213-233. doi: 10.1007/978-1-0716-2281-0_16.
Reda A, Stukenborg JB, Deng Q
Methods Mol Biol. 2022; 2490:235-249. doi: 10.1007/978-1-0716-2281-0_17.
Liu Q, Tang B, Zhu Z, Kraft P, Deng Q, Stener-Victorin E, Jiang X
Diabetologia. 2022 Sep;65(9):1483-1494. doi: 10.1007/s00125-022-05746-x.
Ma Q, Xiao Y, Xu W, Wang M, Li S, Yang Z, Xu M, Zhang T, Zhang ZN, Hu R, Su Q, Yuan F, Xiao T, Wang X, He Q, Zhao J, Chen ZJ, Sheng Z, Chai M, Wang H, Shi W, Deng Q#, Cheng X#, Li W# (# shared corresponding author)
Nat Commun. 2022 Jul 16;13(1):4142. doi: 10.1038/s41467-022-31829-9.
Our work is highlighted in Nature reviews endocrinology and Science Signaling
Elastic dosage compensation by X-chromosome upregulation
Lentini A, Cheng H, Noble JC, Papanicolaou N, Coucoravas C, Andrews N, Deng Q, Enge M, Reinius B
Nat Commun, 2022 Apr 6;13(1):1854. doi: 10.1038/s41467-022-29414-1.
Liu Q, Zhu Z, Kraft P, Deng Q, Stener-Victorin E, Jiang X
BMC Med. 2022 Feb 11;20(1):66. doi: 10.1186/s12916-022-02238-y.
2021
Dongqing Li, Shangli Cheng, Yu Pei, Pehr Sommar, Jaanika Kärner, Eva K Herter, Maria A Toma, Letian Zhang, Kim Pham, Yuen Ting Cheung, Zhuang Liu, Xingqi Chen, Liv Eidsmo, Qiaolin Deng#, Ning Xu Landén# (# shared corresponding author)
J Invest Dermatol . 2021 Sep 15;S0022-202X(21)02167-9. doi: 10.1016/j.jid.2021.07.176.
O. C. Bedoya-Reina, W. Li, M. Arceo, M. Plescher, P. Bullova, H. Pui, M. Kaucka, P. Kharchenko, T. Martinsson, J. Holmberg, I. Adameyko, Q. Deng, C. Larsson, C. C. Juhlin, P. Kogner & S. Schlisio
Nat Commun. 2021 Sep 7;12: 5309. https://doi.org/10.1038/s41467-021-24870-7.
Julio Aguila, Shangli Cheng, Nigel Kee, Ming Cao, Menghan Wang, Qiaolin Deng#, Eva Hedlund# (# shared corresponding author)
Front Mol Neurosci. 2021 Jul 8;14:699562. doi: 10.3389/fnmol.2021.699562.
Epigenetic inheritance of polycystic ovary syndrome - challenges and opportunities for treatment
Elisabet Stener-Victorin, Qiaolin Deng
Nat Rev Endocrinol. 2021 Jul 7. doi: 10.1038/s41574-021-00517-x.
Featured in the cover
Transmission of polycystic ovary syndrome via epigenetic inheritance
Elisabet Stener-Victorin, Qiaolin Deng
Trends Mol Med. 2021 Jun 11;S1471-4914(21)00129-5. doi: 10.1016/j.molmed.2021.05.005.
Xia Jiang, Qiaolin Deng, Elisabet Stener-Victorin
Hum Reprod. 2021 May 29;deab119. doi: 10.1093/humrep/deab119.
Sanjiv Risal, Maria Manti, Haojiang Lu, Romina Fornes, Henrik Larsson, Anna Benrick, Qiaolin Deng, Carolyn E. Cesta, Mina A. Rosenqvist & Elisabet Stener-Victorin
Transl Psychiatry. 2021 Jan 13;11(1):45. doi: 10.1038/s41398-020-01183-9.
2020
Maria Manti, Han-Pin Pui, Sonja Edström, Sanjiv Risal, Haojiang Lu, Eva Lindgren, Claes Ohlsson, Elisabet Jerlhag, Anna Benrick, Qiaolin Deng, Elisabet Stener-Victorin
FASEB J. 2020 Nov;34(11):14440-14457. doi: 10.1096/fj.202001060R.
Susanne Nichterwitz, Jik Nijssen, Helena Storvall, Christoph Schweingruber, Laura Helen Comley, Ilary Allodi, Mirjam van der Lee, Qiaolin Deng, Rickard Sandberg, Eva Hedlund
Genome Res. 2020 Aug;30(8):1083-1096. doi: 10.1101/gr.265017.120.
2019
Sanjiv Risal, Yu Pei, Haojiang Lu, Maria Manti, Romina Fornes, Han-Pin Pui, Zhiyi Zhao, Julie Massart, Claes Ohlsson, Eva Lindgren, Nicolas Crisosto, Manuel Maliqueo, Barbara Echiburú, Amanda Ladrón de Guevara, Teresa Sir-Petermann, Henrik Larsson, Mina A Rosenqvist, Carolyn E Cesta, Anna Benrick, Qiaolin Deng, Elisabet Stener-Victorin
Nat Med. 2019 Dec;25(12):1894-1904. doi: 10.1038/s41591-019-0666-1.
Intussusceptive Vascular Remodeling Precedes Pathological Neovascularization.
Ali Z, Mukwaya A, Biesemeier A, Ntzouni M, Ramsköld D, Giatrellis S, Mammadzada P, Cao R, Lennikov A, Marass M, Gerri C, Hildesjö C, Taylor M, Deng Q, Peebo B, Del Peso L, Kvanta A, Sandberg R, Schraermeyer U, Andre H, Steffensen JF, Lagali N, Cao Y, Kele J, Jensen LD
Arterioscler Thromb Vasc Biol. 2019 Jul;39(7):1402-1418. doi: 10.1161/ATVBAHA.118.312190.
Shangli Cheng, Yu Pei, Liqun He, Guangdun Peng, Björn Reinius, Patrick P L Tam, Naihe Jing, Qiaolin Deng
Cell Rep. 2019 Mar 5;26(10):2593-2607.e3. doi: 10.1016/j.celrep.2019.02.031.
2018
Amol K Bhandage, Zhe Jin, Sergiy V Korol, Qiujin Shen, Yu Pei, Qiaolin Deng, Daniel Espes, Per-Ola Carlsson, Masood Kamali-Moghaddam, Bryndis Birnir
EBioMedicine. 2018 Apr;30:283-294. doi: 10.1016/j.ebiom.2018.03.019.
Susanne Nichterwitz, Julio Aguila Benitez, Rein Hoogstraaten, Qiaolin Deng, Eva Hedlund
Methods Mol Biol. 2018;1649:95-110. doi: 10.1007/978-1-4939-7213-5_6.
Single-cell RNA sequencing: Technical advancements and biological applications
Eva Hedlund, Qiaolin Deng
Mol Aspects Med. 2018 Feb;59:36-46. doi: 10.1016/j.mam.2017.07.003.
2017
Revealing allele-specific gene expression by single-cell transcriptomics.
Julio Aguila Benitez, Shangli Cheng, Qiaolin Deng
Int J Biochem Cell Biol. 2017 Sep;90:155-160. doi: 10.1016/j.biocel.2017.05.029.
2016
Intussusceptive Vascular Remodeling Precedes Pathological Neovascularization.
Björn Reinius, Jeff E Mold, Daniel Ramsköld, Qiaolin Deng, Per Johnsson, Jakob Michaëlsson, Jonas Frisén, Rickard Sandberg
Nat Genet. 2016 Nov;48(11):1430-1435. doi: 10.1038/ng.3678.
Geng Chen, John Paul Schell, Julio Aguila Benitez, Sophie Petropoulos, Marlene Yilmaz, Björn Reinius, Zhanna Alekseenko, Leming Shi, Eva Hedlund, Fredrik Lanner, Rickard Sandberg, Qiaolin Deng
Genome Res. 2016 Oct;26(10):1342-1354. doi: 10.1101/gr.201954.115.
Hélène Doucet-Beaupré, Catherine Gilbert, Marcos Schaan Profes, Audrey Chabrat, Consiglia Pacelli, Nicolas Giguère, Véronique Rioux, Julien Charest, Qiaolin Deng, Ariadna Laguna, Johan Ericson, Thomas Perlmann, Siew-Lan Ang, Francesca Cicchetti, Martin Parent, Louis-Eric Trudeau, Martin Lévesque
Proc Natl Acad Sci U S A. 2016 Jul 26;113(30):E4387-96. doi: 10.1073/pnas.1520387113.
Susanne Nichterwitz, Geng Chen, Julio Aguila Benitez, Marlene Yilmaz, Helena Storvall, Ming Cao, Rickard Sandberg, Qiaolin Deng, Eva Hedlund
Nat Commun. 2016 Jul 8;7:12139. doi: 10.1038/ncomms12139.
Eva Hedlund, Laure Belnoue, Spyridon Theofilopoulos, Carmen Salto, Chris Bye, Clare Parish, Qiaolin Deng, Banafsheh Kadkhodaei, Johan Ericson, Ernest Arenas, Thomas Perlmann, András Simon
Sci Rep. 2016 Jun 1;6:26448. doi: 10.1038/srep26448.
Loss of CSL Unlocks a Hypoxic Response and Enhanced Tumor Growth Potential in Breast Cancer Cells.
Eike-Benjamin Braune, Yat Long Tsoi, Yee Peng Phoon, Sebastian Landor, Helena Silva Cascales, Daniel Ramsköld, Qiaolin Deng, Arne Lindqvist, Xiaojun Lian, Cecilia Sahlgren, Shao-Bo Jin, Urban Lendahl
Stem Cell Reports. 2016 May 10;6(5):643-651. doi: 10.1016/j.stemcr.2016.03.004.
Single-Cell RNA-Seq Reveals Lineage and X Chromosome Dynamics in Human Preimplantation Embryos.
Sophie Petropoulos, Daniel Edsgärd, Björn Reinius, Qiaolin Deng, Sarita Pauliina Panula, Simone Codeluppi, Alvaro Plaza Reyes, Sten Linnarsson, Rickard Sandberg, Fredrik Lanner
Cell. 2016 May 5;165(4):1012-26. doi: 10.1016/j.cell.2016.03.023. Epub 2016 Apr 7.
Electrophysiological, transcriptomic and morphologic profiling of single neurons using Patch-seq
Cathryn R Cadwell, Athanasia Palasantza, Xiaolong Jiang, Philipp Berens, Qiaolin Deng, Marlene Yilmaz, Jacob Reimer, Shan Shen, Matthias Bethge, Kimberley F Tolias, Rickard Sandberg, Andreas S Tolias
Nat Biotechnol. 2016 Feb;34(2):199-203. doi: 10.1038/nbt.3445.
2015
Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease.
Ariadna Laguna, Nicoletta Schintu, André Nobre, Alexandra Alvarsson, Nikolaos Volakakis, Jesper Kjaer Jacobsen, Marta Gómez-Galán, Elena Sopova, Eliza Joodmardi, Takashi Yoshitake, Qiaolin Deng, Jan Kehr, Johan Ericson, Per Svenningsson, Oleg Shupliakov, Thomas Perlmann
Nat Neurosci. 2015 Jun;18(6):826-35. doi: 10.1038/nn.4004.
2014
Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo.
Petter S Woll, Una Kjällquist, Onima Chowdhury, Helen Doolittle, David C Wedge, Supat Thongjuea, Rikard Erlandsson, Mtakai Ngara, Kristina Anderson, Qiaolin Deng, Adam J Mead, Laura Stenson, Alice Giustacchini, Sara Duarte, Eleni Giannoulatou, Stephen Taylor, Mohsen Karimi, Christian Scharenberg, Teresa Mortera-Blanco, Iain C Macaulay, Sally-Ann Clark, Ingunn Dybedal, Dag Josefsen, Pierre Fenaux, Peter Hokland, Mette S Holm, Mario Cazzola, Luca Malcovati, Sudhir Tauro, David Bowen, Jacqueline Boultwood, Andrea Pellagatti, John E Pimanda, Ashwin Unnikrishnan, Paresh Vyas, Gudrun Göhring, Brigitte Schlegelberger, Magnus Tobiasson, Gunnar Kvalheim, Stefan N Constantinescu, Claus Nerlov, Lars Nilsson, Peter J Campbell, Rickard Sandberg, Elli Papaemmanuil, Eva Hellström-Lindberg, Sten Linnarsson, Sten Eirik W Jacobsen
Cancer Cell. 2014 Jun 16;25(6):794-808. doi: 10.1016/j.ccr.2014.03.036.
Single-cell RNA-seq reveals dynamic, random monoallelic gene expression in mammalian cells.
Qiaolin Deng, Daniel Ramsköld, Björn Reinius, Rickard Sandberg
Science. 2014 Jan 10;343(6167):193-6. doi: 10.1126/science.1245316.
2013 and before
Charlotta Böiers, Joana Carrelha, Michael Lutteropp, Sidinh Luc, Joanna C A Green, Emanuele Azzoni, Petter S Woll, Adam J Mead, Anne Hultquist, Gemma Swiers, Elisa Gomez Perdiguero, Iain C Macaulay, Luca Melchiori, Tiago C Luis, Shabnam Kharazi, Tiphaine Bouriez-Jones, Qiaolin Deng, Annica Pontén, Deborah Atkinson, Christina T Jensen, Ewa Sitnicka, Frederic Geissmann, Isabelle Godin, Rickard Sandberg, Marella F T R de Bruijn, Sten Eirik W Jacobsen
Cell Stem Cell. 2013 Nov 7;13(5):535-48. doi: 10.1016/j.stem.2013.08.012.
Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells.
Daniel Ramsköld, Shujun Luo, Yu-Chieh Wang, Robin Li, Qiaolin Deng, Omid R Faridani, Gregory A Daniels, Irina Khrebtukova, Jeanne F Loring, Louise C Laurent, Gary P Schroth, Rickard Sandberg
Nat Biotechnol. 2012 Aug;30(8):777-82. doi: 10.1038/nbt.2282.
Specific and integrated roles of Lmx1a, Lmx1b and Phox2a in ventral midbrain development.
Qiaolin Deng, Elisabet Andersson, Eva Hedlund, Zhanna Alekseenko, Eva Coppola, Lia Panman, James H Millonig, Jean-Francois Brunet, Johan Ericson, Thomas Perlmann
Development. 2011 Aug;138(16):3399-408. doi: 10.1242/dev.065482.
Transcription factor-induced lineage selection of stem-cell-derived neural progenitor cells.
Lia Panman, Elisabet Andersson, Zhanna Alekseenko, Eva Hedlund, Nigel Kee, Jamie Mong, Christopher W Uhde, Qiaolin Deng, Rickard Sandberg, Lawrence W Stanton, Johan Ericson, Thomas Perlmann
Cell Stem Cell. 2011 Jun 3;8(6):663-75. doi: 10.1016/j.stem.2011.04.001..
Identification of intrinsic determinants of midbrain dopamine neurons.
Elisabet Andersson, Ulrika Tryggvason, Qiaolin Deng, Stina Friling, Zhanna Alekseenko, Benoit Robert, Thomas Perlmann, Johan Ericson
Cell. 2006 Jan 27;124(2):393-405. doi: 10.1016/j.cell.2005.10.037.